Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.65 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.65 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CD69 | Q07108 | 1/20 | 0.48 |
| ▸ | BMP2 | P12643 | 1/20 | 0.45 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | SHH | Q15465 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875721 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL9403699 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL7722124 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL7722131 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL15334244 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL25480942 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL7718406 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL7715068 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL19246175 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 | |
| SCHEMBL7715066 | 1.00 | MAPK1 (1.00) | MAPK1LGALS8LGALS3LGALS4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994855-B2 | Compositions and methods for modulating growth hormone receptor expression | IONIS PHARMACEUTICALS, INC. (US) | 2018-06-12 | — | — | US | disclosed |
| EP-2920307-B1 | ANTI APOB ANTISENSE CONJUGATE COMPOUNDS | ROCHE INNOVATION CT COPENHAGEN AS (DK) | 2018-05-02 | — | — | EP | disclosed |
| US-9879265-B2 | Oligonucleotide conjugates | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2018-01-30 | — | — | US | disclosed |
| US-20170166899-A1 | COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION | IONIS PHARMACEUTICALS, INC. (US) | 2017-06-15 | — | — | US | disclosed |