Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SI | P14410 | 2/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | GUSB | P08236 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18973648 | 0.92 | MEN1 (0.51) | MEN1MAPTPKMKMT2AMGAM | |
| SCHEMBL18973676 | 0.88 | MEN1 (0.45) | MEN1MAPTPKMKMT2AMGAM | |
| SCHEMBL18973662 | 0.87 | MEN1 (0.46) | MEN1MAPTPKMKMT2AMGAM | |
| SCHEMBL18973678 | 0.87 | MAPT (0.50) | LMNARAB9AMEN1MAPTPKM | |
| SCHEMBL18973831 | 0.86 | KMT2A (0.65) | LMNAMEN1MAPTPKMKMT2A | |
| SCHEMBL18973650 | 0.85 | KMT2A (0.51) | LMNAMEN1MAPTPKMKMT2A | |
| SCHEMBL21175063 | 0.81 | MEN1 (0.46) | LMNARAB9AMEN1MAPTPKM | |
| SCHEMBL18973651 | 0.81 | MEN1 (0.46) | MEN1MAPTPKMKMT2AMGAM | |
| SCHEMBL18962412 | 0.81 | KMT2A (0.47) | MEN1MAPTPKMKMT2AMGAM | |
| SCHEMBL18973675 | 0.81 | MAPT (0.50) | LMNARAB9AMEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098731-A1 | 4-PHENYL-4-OXOBUTANOIC ACID DERIVATIVE | 株式会社 東北テクノアーチ | 2017-06-15 | — | — | WO | disclosed |