Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SI | P14410 | 2/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18973662 | 0.92 | MEN1 (0.46) | MEN1KMT2AMAPTPKMF7 | |
| SCHEMBL18973649 | 0.92 | LMNA (0.47) | MEN1KMT2AMAPTPKMF7 | |
| SCHEMBL18973831 | 0.91 | KMT2A (0.65) | MEN1KMT2AMAPTPKMMGAM | |
| SCHEMBL18973650 | 0.91 | KMT2A (0.51) | MEN1KMT2AMAPTPKMF7 | |
| SCHEMBL18973676 | 0.90 | MEN1 (0.45) | MEN1KMT2AMAPTPKMF7 | |
| SCHEMBL18973678 | 0.90 | MAPT (0.50) | MEN1KMT2AMAPTPKMMGAM | |
| SCHEMBL21175080 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPTPKMF7 | |
| SCHEMBL18973651 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPTPKMF7 | |
| SCHEMBL18962412 | 0.85 | KMT2A (0.47) | MEN1KMT2AMAPTPKMF7 | |
| SCHEMBL6831865 | 0.85 | F7 (0.54) | MEN1KMT2AMAPTPKMF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098731-A1 | 4-PHENYL-4-OXOBUTANOIC ACID DERIVATIVE | 株式会社 東北テクノアーチ | 2017-06-15 | — | — | WO | disclosed |