Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18974742 | 0.88 | SMN1; SMN2 (0.46) | KDM4EMEN1KMT2APOLBLMNA | |
| SCHEMBL8161375 | 0.87 | CA12 (0.49) | KDM4EMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL17912 | 0.87 | KDM4E (0.56) | KDM4EMEN1KMT2APOLBLMNA | |
| SCHEMBL14962823 | 0.86 | SMN1; SMN2 (0.45) | KDM4EMEN1KMT2APOLBLMNA | |
| SCHEMBL14962824 | 0.85 | SMN1; SMN2 (0.44) | KDM4EMEN1KMT2APOLBLMNA | |
| SCHEMBL26736145 | 0.84 | SMN1; SMN2 (0.62) | KDM4EMEN1KMT2APOLBLMNA | |
| SCHEMBL12516724 | 0.83 | ESR1 (0.53) | MEN1KMT2ALMNASMN1; SMN2CYP3A4 | |
| SCHEMBL15803992 | 0.82 | CA12 (0.45) | KDM4EMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL19978962 | 0.82 | KDM4E (0.52) | KDM4EMEN1KMT2APOLBLMNA | |
| SCHEMBL8507007 | 0.81 | SMN1; SMN2 (0.57) | KDM4EMEN1KMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521707-B1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2017-06-14 | — | — | EP | disclosed |