Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161375 | 0.93 | CA12 (0.49) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL22182453 | 0.90 | ESR1 (0.47) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL23813386 | 0.90 | MAOB (0.48) | SMN1; SMN2KMT2AMEN1MAOAMAOB | |
| SCHEMBL15803992 | 0.88 | CA12 (0.45) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL14962795 | 0.86 | MAOA (0.46) | SMN1; SMN2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL12516724 | 0.85 | ESR1 (0.53) | SMN1; SMN2KMT2AMEN1ALDH1A1HTT | |
| SCHEMBL13020406 | 0.85 | CA12 (0.42) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL18974742 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL14962823 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1KDM4EPOLB | |
| SCHEMBL4278557 | 0.82 | CA12 (0.49) | SMN1; SMN2KDM4EALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861111-A | Method for isomerization of arylpropargyl ether monomers and uses therefor | DEXTER CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |