Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20508095 | 0.83 | WNT3A (0.52) | WNT3AMAPK1 | |
| SCHEMBL20508014 | 0.81 | WNT3A (0.47) | WNT3AMAPK1 | |
| SCHEMBL18962618 | 0.79 | WNT3A (0.40) | WNT3APORCN | |
| SCHEMBL20507844 | 0.79 | WNT3A (0.56) | WNT3AMAPK1PORCN | |
| SCHEMBL20507995 | 0.79 | WNT3A (0.55) | WNT3AMAPK1PORCN | |
| SCHEMBL20508043 | 0.78 | WNT3A (0.49) | WNT3AMAPK1 | |
| SCHEMBL20508185 | 0.77 | MAPK1 (0.47) | WNT3AMAPK1 | |
| SCHEMBL20508075 | 0.77 | MAPK1 (0.53) | WNT3AMAPK1PORCN | |
| SCHEMBL18962572 | 0.71 | WNT3A (0.54) | WNT3APORCN | |
| SCHEMBL18962700 | 0.69 | WNT3A (0.38) | WNT3AMAPK1PORCN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097216-A9 | FIVE-MEMBERED HETEROCYCLIC AMIDES WNT PATHWAY INHIBITOR | 杭州雷索药业有限公司 | 2017-11-23 | — | — | WO | disclosed |
| WO-2017097216-A1 | FIVE-MEMBERED HETEROCYCLIC AMIDES WNT PATHWAY INHIBITOR | 杭州雷索药业有限公司 | 2017-06-15 | — | — | WO | disclosed |