Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTR1E | P28566 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.43 |
| ▸ | DNM1L | O00429 | 1/20 | 0.43 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7744394 | 0.81 | NPSR1 (0.64) | NPSR1MAPTPTGDR2SMN1; SMN2MAPK1 | |
| SCHEMBL147011 | 0.77 | NPSR1 (0.65) | NPSR1MAPTPTGDR2MAPK1CYP3A4 | |
| SCHEMBL147214 | 0.76 | MAPT (0.67) | NPSR1MAPTPTGDR2LMNARECQL | |
| SCHEMBL3077688 | 0.75 | P2RY14 (0.54) | MAPTP2RY14LMNARECQLKCNJ6 | |
| SCHEMBL144387 | 0.75 | NPSR1 (0.76) | NPSR1MAPTPTGDR2MAPK1HTR1E | |
| SCHEMBL1902360 | 0.75 | KMT2A (0.57) | NPSR1MAPTCYP3A4CYP2C9P2RY14 | |
| SCHEMBL146791 | 0.74 | NPSR1 (0.78) | NPSR1MAPTPTGDR2MAPK1FLT1 | |
| SCHEMBL13744085 | 0.72 | RXFP1 (0.39) | — | |
| SCHEMBL1900773 | 0.70 | NPSR1 (0.90) | NPSR1MAPTPTGDR2SMN1; SMN2MAPK1 | |
| SCHEMBL24798287 | 0.69 | BRD4 (0.59) | SMN1; SMN2CYP3A4CYP2C9P2RY14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252156-B1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | UCL BUSINESS PLC (GB) | 2011-05-04 | — | — | EP | disclosed |