Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147011 | 0.88 | NPSR1 (0.65) | NPSR1MAPTP2RY14NPC1RAB9A | |
| SCHEMBL144387 | 0.87 | NPSR1 (0.76) | NPSR1MAPTP2RY14NPC1RAB9A | |
| SCHEMBL3077688 | 0.86 | P2RY14 (0.54) | MAPTP2RY14L3MBTL1TP53LMNA | |
| SCHEMBL1900773 | 0.83 | NPSR1 (0.90) | NPSR1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL147214 | 0.82 | MAPT (0.67) | NPSR1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL1897475 | 0.81 | NPSR1 (0.48) | NPSR1MAPTP2RY14MAPK1HTR1E | |
| SCHEMBL146791 | 0.80 | NPSR1 (0.78) | NPSR1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL7744959 | 0.79 | NPSR1 (1.00) | NPSR1MAPTP2RY14NPC1RAB9A | |
| SCHEMBL1902360 | 0.79 | KMT2A (0.57) | NPSR1MAPTP2RY14NPC1RAB9A | |
| SCHEMBL7746883 | 0.78 | NPSR1 (0.94) | NPSR1MAPTMAPK1HTR1ES1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252156-A1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | University College London (GB) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001057024-A1 | BLOCKADE OF VOLTAGE DEPENDENT SODIUM CHANNELS | UNIVERSITY COLLEGE LONDON (GB) | 2001-08-09 | — | — | WO | disclosed |