SCHEMBL18975253

SCHEMBL18975253

C#CC#CCCCCCCCCCCCCCCO

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.34
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SELP P16109 1/20 0.33
HMGCR P04035 2/20 0.32
PTPN7 P35236 1/20 0.32
LMNA P02545 2/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4062798 1.00 MIF (0.34) MIFALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL4053148 0.97
SCHEMBL18881113 0.91 SELP (0.35) MIFALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL15529274 0.90
SCHEMBL1168913 0.84 HMGCR (0.41) MIFALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL1169581 0.84 HMGCR (0.41) MIFALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL1765934 0.84 HMGCR (0.41) MIFALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL1168708 0.84 HMGCR (0.41) MIFALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL1169234 0.84 HMGCR (0.41) MIFALDH1A1KDM4ECYP1A2CYP3A4
SCHEMBL302841 0.81 ALDH1A1 (0.39) ALDH1A1KDM4ECYP1A2CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170166679-A1 POLYURETHANE MATERIALS FORMED FROM UNSATURATED PLANT OILS VIA AN ALKYNE ZIPPER REACTION INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-06-15 US disclosed