Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22550665 | 1.00 | KDM4E (0.48) | KDM4EPTPN1TRPV1TRPA1SLC6A2 | |
| SCHEMBL22446639 | 1.00 | KDM4E (0.48) | KDM4EPTPN1TRPV1TRPA1SLC6A2 | |
| SCHEMBL12164594 | 0.85 | KDM4E (0.52) | KDM4ESLC6A2SLC6A4 | |
| SCHEMBL20857227 | 0.79 | KDM4E (0.60) | KDM4ESLC6A2SLC6A4 | |
| SCHEMBL3071851 | 0.79 | KDM4E (0.60) | KDM4ESLC6A2SLC6A4 | |
| SCHEMBL1687120 | 0.79 | THRB (0.37) | KDM4EPTPN1TRPV1TRPA1 | |
| SCHEMBL7296784 | 0.78 | — | — | |
| SCHEMBL6484888 | 0.74 | — | — | |
| SCHEMBL1790073 | 0.73 | TRPV1 (0.39) | KDM4EPTPN1TRPV1TRPA1 | |
| SCHEMBL1900252 | 0.73 | THRB (0.40) | KDM4EPTPN1TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386953-B1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2020-10-21 | — | — | EP | disclosed |
| WO-2017098038-A1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-06-15 | — | — | WO | disclosed |