Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975556 | 0.92 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14639021 | 0.81 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1371669 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL18975305 | 0.77 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2AKDM4EUSP2 | |
| Hydrochloric Acid SCHEMBL17271453 | 0.76 | TP53 (0.46) | PADI1PADI4ALDH1A1SMN1; SMN2CHRM5 | |
| SCHEMBL18975282 | 0.74 | TP53 (0.45) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL24090587 | 0.74 | CHRM5 (0.45) | PADI1PADI4ALDH1A1SMN1; SMN2CHRM5 | |
| Trifluoroacetic Acid SCHEMBL28507615 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL9643851 | 0.73 | MEN1 (0.50) | MAPTMEN1KMT2AUSP2 | |
| SCHEMBL8594804 | 0.73 | CHRM5 (0.49) | ALDH1A1SMN1; SMN2CHRM5CHRM3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386953-B1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2020-10-21 | — | — | EP | disclosed |
| WO-2017098038-A1 | CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2017-06-15 | — | — | WO | disclosed |