Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975997 | 0.82 | SIRT1 (0.35) | SIRT1 | |
| SCHEMBL16320360 | 0.79 | BTK (0.33) | — | |
| SCHEMBL16320337 | 0.78 | BTK (0.40) | — | |
| SCHEMBL16319986 | 0.68 | LIMK1 (0.37) | SIRT1 | |
| SCHEMBL16339428 | 0.67 | BTK (0.41) | — | |
| SCHEMBL19279075 | 0.67 | LIMK1 (0.36) | SIRT1 | |
| SCHEMBL19426953 | 0.67 | BTK (0.46) | — | |
| SCHEMBL20303986 | 0.66 | BTK (0.43) | — | |
| SCHEMBL22837857 | 0.65 | BTK (0.43) | — | |
| SCHEMBL22837877 | 0.65 | BTK (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013814-B1 | SUBSTITUTED TETRAHYDROCARBAZOLE AND CARBAZOLE CARBOXAMIDE COMPOUNDS USEFUL AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-06-14 | — | — | EP | disclosed |