Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976316 | 0.84 | AR (0.43) | TP53ARPOLB | |
| SCHEMBL18976172 | 0.80 | AR (0.46) | TP53RXFP1ARTHRBLMNA | |
| SCHEMBL20581240 | 0.79 | AR (0.51) | TP53RXFP1ARTHRBLMNA | |
| SCHEMBL20581396 | 0.78 | AR (0.52) | TP53RXFP1ARTHRBLMNA | |
| SCHEMBL21941150 | 0.77 | AR (0.44) | TP53RXFP1ARTHRBLMNA | |
| SCHEMBL21940850 | 0.76 | AR (0.45) | TP53RXFP1ARTHRBLMNA | |
| SCHEMBL18975784 | 0.75 | AR (0.48) | TP53HRH3ARLMNACNR2 | |
| SCHEMBL20581386 | 0.70 | TP53 (0.43) | TP53HRH3ARTHRBPOLB | |
| SCHEMBL20581339 | 0.70 | AR (0.42) | TP53RXFP1ARTHRBLMNA | |
| SCHEMBL20581193 | 0.68 | AR (0.61) | TP53HRH3RXFP1ARTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |