Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20581240 | 0.86 | AR (0.51) | ARRXFP1THRBTP53LMNA | |
| SCHEMBL20527335 | 0.85 | LMNA (0.44) | RXFP1THRBTP53LMNAPOLB | |
| SCHEMBL20581396 | 0.85 | AR (0.52) | ARRXFP1THRBTP53LMNA | |
| SCHEMBL21451882 | 0.83 | PTPN1 (0.46) | POLBNPC1RAB9AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20527158 | 0.82 | PTPN1 (0.44) | POLBHTTNPC1RAB9AALDH1A1 | |
| SCHEMBL21941150 | 0.81 | AR (0.44) | ARRXFP1THRBTP53LMNA | |
| SCHEMBL18574371 | 0.81 | RXFP1 (0.42) | RXFP1TP53LMNAALDH1A1MAPT | |
| SCHEMBL18976491 | 0.80 | TP53 (0.41) | ARRXFP1THRBTP53LMNA | |
| SCHEMBL21940850 | 0.80 | AR (0.45) | ARRXFP1THRBTP53LMNA | |
| Hydrochloric Acid SCHEMBL30944505 | 0.80 | RXFP1 (0.41) | RXFP1TP53LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098257-A1 | PBD ANTIBACTERIAL AGENTS | KING'S COLLEGE LONDON (GB) | 2017-06-15 | — | — | WO | disclosed |