Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAUR | Q03405 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MASP2 | O00187 | 1/20 | 0.59 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | KHK | P50053 | 1/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.55 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30682553 | 1.00 | PLAUR (1.00) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL30588935 | 0.79 | KMT2A (0.97) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL25367120 | 0.79 | KMT2A (0.97) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL16403339 | 0.76 | PLAUR (0.61) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29010071 | 0.76 | PLAUR (0.61) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1029154 | 0.76 | PLAUR (0.61) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL30170557 | 0.76 | PLAUR (0.61) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL16065887 | 0.76 | PLAUR (0.61) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1589916 | 0.76 | PLAUR (0.61) | PLAURMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28487096 | 0.76 | PLAUR (0.61) | PLAURMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813593-A | 3-aminoquinoxalinone compound and synthesis method thereof | 郑州泰基鸿诺医药股份有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-115747838-A | Method for synthesizing amino-substituted quinoxalinone compound through electrochemical reaction | 南京师范大学 | 2023-03-07 | — | — | CN | claimed |
| CN-105001169-A | Synthetic method for 3-aminoquinoxaline-2(1H)-ketone compound | UNIV HUAQIAO | 2015-10-28 | — | — | CN | claimed |
| EP-1649857-A2 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2006-04-26 | — | — | EP | claimed |
| US-20050054650-A1 | Use of glutamate antagonists for the treatment of cancer | IKONOMIDOU HRISSANTHI (DE) | 2005-03-10 | — | — | US | claimed |
| EP-1124553-A1 | NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER | Ikonomidou, Hrissanthi (DE) | 2001-08-22 | — | — | EP | claimed |
| EP-1002535-A1 | New use of glutamate antagonists for the treatment of cancer | Ikonomidou, Hrissanthi (DE) | 2000-05-24 | — | — | EP | claimed |
| WO-2000024395-A1 | NEW USE OF GLUTAMATE ANTAGONISTS FOR THE TREATMENT OF CANCER | IKONOMIDOU HRISSANTHI (DE) | 2000-05-04 | — | — | WO | claimed |
| US-5633255-A | RESPIRATORY SYSTEM DISORDERS; ACID HYDROLYSIS; ALKYLATION | PIERRE FABRE MEDICAMENT (FR) | 1997-05-27 | — | — | US | claimed |
| EP-0663903-B1 | 1,2-DIHYDRO-2-OXO-3-AMINO QUINOXALINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION IN THERAPY | PF MEDICAMENT (FR) | 1997-04-23 | — | — | EP | claimed |
| CN-116813593-A | 3-aminoquinoxalinone compound and synthesis method thereof | 郑州泰基鸿诺医药股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116813593-A | 3-aminoquinoxalinone compound and synthesis method thereof | 郑州泰基鸿诺医药股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116813593-A | 3-aminoquinoxalinone compound and synthesis method thereof | 郑州泰基鸿诺医药股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-109160903-B | Photocatalytic preparation method of 3-aminoquinoxaline-2 (1H) -ketone compound | 曲阜师范大学 | 2021-07-16 | — | — | CN | disclosed |
| CN-107973755-B | Preparation method of 3-acetamido quinoxalinone derivative | 滨州学院 | 2020-12-29 | — | — | CN | disclosed |
| WO-1996004288-A1 | GLYCINE RECEPTOR ANTAGONIST PHARMACOPHORE | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE OREGON (US) | 1996-02-15 | — | — | WO | disclosed |
| EP-0663903-A1 | 1,2-DIHYDRO-2-OXO-3-AMINO QUINOXALINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION IN THERAPY. | PF MEDICAMENT (FR) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994007870-A1 | 1,2-DIHYDRO-2-OXO-3-AMINO QUINOXALINE DERIVATIVES, PREPARATION THEREOF AND APPLICATION IN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 1994-04-14 | — | — | WO | disclosed |
| EP-0185618-A2 | Isoindolines, process for their manufacture and their use | CIBA-GEIGY AG (CH) | 1986-06-25 | — | — | EP | disclosed |
| US-3963694-A | AZO PIGMENTS, POLYESTERS, CELLULOSE ETHERS AND ESTERS | CIBA-GEIGY CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |