SCHEMBL29010071

SCHEMBL29010071

O=c1[nH]c2ccccc2nc1F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAUR Q03405 1/20 0.61
KDM4E B2RXH2 12/20 0.61
ALDH1A1 P00352 7/20 0.61
KHK P50053 1/20 0.61
RAB9A P51151 9/20 0.58
NPC1 O15118 8/20 0.58
HPGD P15428 5/20 0.54
HSD17B10 Q99714 4/20 0.54
GAA P10253 2/20 0.54
MAPK1 P28482 1/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
MAPT P10636 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HTT P42858 3/20 0.53
PYGM P11217 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
ABCB11 O95342 1/20 0.52
TP53 P04637 1/20 0.52
PKM P14618 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL853992 0.76 PLAUR (0.61) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL30170557 0.76 PLAUR (0.61) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL28487096 0.76 PLAUR (0.61) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL29124805 0.76 PLAUR (0.61) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL1029154 0.76 PLAUR (0.61) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL30682553 0.76 PLAUR (1.00) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL30617972 0.76 PLAUR (0.61) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL16403339 0.76 PLAUR (0.61) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL1589916 0.76 PLAUR (0.61) PLAURKDM4EALDH1A1KHKRAB9A
SCHEMBL1897684 0.76 PLAUR (1.00) PLAURKDM4EALDH1A1KHKRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117585960-A Environment-friendly green concrete 江苏立浩建材科技有限公司 2024-02-23 CN claimed
US-20250295642-A1 FLUOROQUINOXALINONE DERIVATIVE FOR SELECTIVELY INHIBITING PARP1 MEDSHINE DISCOVERY INC. (CN) 2025-09-25 US disclosed
EP-4524142-A1 FLUOROQUINOXALINONE DERIVATIVE FOR SELECTIVELY INHIBITING PARP1 Medshine Discovery Inc. (CN) 2025-03-19 EP disclosed
CN-119110801-A Fluoroquinoxalinone derivatives which selectively inhibit PARP1 南京明德新药研发有限公司 2024-12-10 CN disclosed
CN-118388879-B Weather-resistant power cable material and preparation method thereof 江苏东峰电缆有限公司 2024-11-26 CN disclosed
CN-118308037-B Heterojunction battery adhesive film and preparation method thereof 昊辰(无锡)塑业有限公司 2024-11-19 CN disclosed
CN-118854519-A Textile fabric with antistatic and antibacterial functions and preparation method thereof 扬州市康诺纺织科技有限公司 2024-10-29 CN disclosed
CN-118388879-A Weather-resistant power cable material and preparation method thereof 江苏东峰电缆有限公司 2024-07-26 CN disclosed
CN-118308037-A Heterojunction battery adhesive film and preparation method thereof 昊辰(无锡)塑业有限公司 2024-07-09 CN disclosed
CN-118290069-A Cold patch asphalt mixture and preparation method and application thereof 北京中路高科交通咨询有限公司 2024-07-05 CN disclosed
CN-117362946-B Nanocellulose modified polyester composite material and preparation method thereof 江苏蜀扬春新材料科技有限公司 2024-05-03 CN disclosed
CN-117585960-A Environment-friendly green concrete 江苏立浩建材科技有限公司 2024-02-23 CN disclosed
CN-117362946-A Nanocellulose modified polyester composite material and preparation method thereof 江苏蜀扬春新材料科技有限公司 2024-01-09 CN disclosed
WO-2023217045-A1 FLUOROQUINOXALINONE DERIVATIVE FOR SELECTIVELY INHIBITING PARP1 南京明德新药研发有限公司 2023-11-16 WO disclosed
CN-116003949-B Wear-resistant sole made of composite material 扬州市天宇鞋业有限公司 2023-09-15 CN disclosed
CN-116676065-A COP whitening improved adhesive for polaroid and preparation method thereof 江西塔益莱高分子材料有限公司 2023-09-01 CN disclosed
CN-116604902-A Heat-insulating fireproof material and preparation method thereof 浙江葆润应用材料有限公司 2023-08-18 CN disclosed
CN-114350304-B Durable high-permeability OCA adhesive and preparation method thereof 江西塔益莱高分子材料有限公司 2023-06-23 CN disclosed
CN-116003949-A Wear-resistant sole made of composite material 扬州市天宇鞋业有限公司 2023-04-25 CN disclosed
CN-115850842-A Weather-resistant flame-retardant PE film and preparation method thereof 扬州联发包装制品有限公司 2023-03-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250295642-A1 FLUOROQUINOXALINONE DERIVATIVE FOR SELECTIVELY INHIBITING PARP1 PARP1, PARP11, PARP15 PLAUR 1637/4885KDM4E 719/4885ALDH1A1 2365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.