Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426045 | 0.97 | MEN1 (0.40) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18878682 | 0.90 | CASP2 (0.41) | HPGDHTTSMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL16724725 | 0.88 | HPGD (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL17750731 | 0.88 | HPGD (0.40) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL18875550 | 0.87 | HPGD (0.35) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL23714576 | 0.87 | KMT2A (0.49) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL25672136 | 0.86 | KMT2A (0.47) | HPGDHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18878679 | 0.85 | HPGD (0.38) | HPGDHTTSMN1; SMN2KMT2AMTNR1A | |
| SCHEMBL337575 | 0.85 | SMN1; SMN2 (0.49) | HPGDHTTSMN1; SMN2KMT2A | |
| SCHEMBL4818636 | 0.85 | SMN1; SMN2 (0.49) | HPGDHTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098029-A1 | ISOBARIC MASS LABELS | ELECTROPHORETICS LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |