SCHEMBL1897777

SCHEMBL1897777

NC(=O)CC1CCC(CC(N)=O)C1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
ALOX5 P09917 4/20 0.41
LMNA P02545 2/20 0.36
PLG P00747 1/20 0.36
PLAT P00750 1/20 0.36
SLC6A12 P48065 3/20 0.33
SLC6A11 P48066 3/20 0.33
SLC6A13 Q9NSD5 3/20 0.33
SLC1A3 P43003 2/20 0.33
SLC1A2 P43004 2/20 0.33
SLC1A1 P43005 2/20 0.33
DGAT1 O75907 2/20 0.33
HSD11B1 P28845 1/20 0.33
SOAT1 P35610 1/20 0.33
ANPEP P15144 1/20 0.32
ENPEP Q07075 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11683426 0.90 ALOX5 (0.45) TDP1ALOX5SLC1A3SLC1A2SLC1A1
SCHEMBL19524948 0.89 TDP1 (0.35) TDP1ALOX5LMNAPLGPLAT
SCHEMBL303265 0.88
SCHEMBL1896079 0.88 TDP1 (0.46) TDP1ALOX5LMNAPLGPLAT
Hydrochloric Acid SCHEMBL2951045 0.86
SCHEMBL1923654 0.85 TDP1 (0.37) TDP1ALOX5LMNAPLGPLAT
SCHEMBL11056909 0.80 TFPI2 (0.35) TDP1ALOX5LMNAKDM4EGMNN
SCHEMBL8890636 0.79 PLG (0.54) TDP1ALOX5LMNAPLGPLAT
SCHEMBL337975 0.79 EPHX2 (0.41) TDP1SLC6A12SLC6A11SLC6A13
SCHEMBL10052648 0.79 TDP1 (0.39) TDP1ALOX5LMNAPLGPLAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2325167-A1 METHOD FOR PRODUCING CARBAMATE COMPOUND Ube Industries, Ltd. (JP) 2011-05-25 EP disclosed