SCHEMBL18979428

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17027858	0.87	DYRK1A (0.47)	DYRK1ALDLRPCSK9GSK3BFLT3
	SCHEMBL17027809	0.86	DYRK1A (0.42)	DYRK1AGSK3BF10WNT1ABL1
	SCHEMBL17027749	0.86	F10 (0.48)	DYRK1AGSK3BF10WNT1
	SCHEMBL18979453	0.83	PIK3CA (0.46)	DYRK1AFLT3KDRF10
	SCHEMBL28754069	0.83	F10 (0.44)	DYRK1AGSK3BF10WNT1
	SCHEMBL23635155	0.76	LDLR (0.38)	DYRK1ALDLRPCSK9GSK3BFLT3
	SCHEMBL18996612	0.73	DYRK1A (0.48)	DYRK1AGSK3BF10WNT1ABL1
	SCHEMBL28941910	0.72	DYRK1A (0.49)	DYRK1AGSK3BF10WNT1
	SCHEMBL17027818	0.72	F10 (0.54)	DYRK1AGSK3BF10WNT1
	SCHEMBL18979456	0.71	F10 (0.61)	DYRK1AGSK3BFLT3F10WNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.