SCHEMBL18979455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18979420	0.90	F10 (0.61)	F10DYRK1AGSK3BWNT1FLT3
	SCHEMBL23635141	0.88	F10 (0.49)	F10DYRK1AGSK3BWNT1MAPK14
	SCHEMBL18979422	0.88	F10 (0.62)	F10DYRK1AGSK3BWNT1FLT3
	SCHEMBL18979456	0.86	F10 (0.61)	F10DYRK1AGSK3BWNT1FLT3
	SCHEMBL4251772	0.77	EPHX2 (0.73)	F10DYRK1AGSK3BWNT1MAPK14
	SCHEMBL31672283	0.77	DEGS1 (0.68)	ABCB1ABCC1SMN1; SMN2DEGS1
	SCHEMBL17040257	0.77	DEGS1 (0.68)	ABCB1ABCC1SMN1; SMN2DEGS1
	SCHEMBL18979436	0.76	SMN1; SMN2 (0.54)	DYRK1AGSK3BABCB1ABCC1SMN1; SMN2
	SCHEMBL18979462	0.75	SMN1; SMN2 (0.52)	DYRK1AGSK3BABCB1ABCC1SMN1; SMN2
	SCHEMBL18979454	0.74	ABCB1 (0.53)	DYRK1AGSK3BWNT1ABCB1ABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.