SCHEMBL1897955

SCHEMBL1897955

O=C1CCC(=O)NOC(=O)CCC(=O)ON1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 3/20 0.40
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8404671 1.00
SCHEMBL377713 0.73
SCHEMBL8362367 0.73 CA1 (0.64) CRBNTSHRALDH1A1LMNATP53
SCHEMBL1458538 0.71
SCHEMBL14777333 0.69 TSHR (0.44) CRBNTSHRALDH1A1LMNATP53
SCHEMBL123182 0.61
SCHEMBL787862 0.61
SCHEMBL6852091 0.59
Succinimide SCHEMBL774 0.58
SCHEMBL1333224 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421785-B2 Delta receptor agonist peptides and use thereof BAR-ILAN UNIVERSITY (IL) 2019-09-24 US disclosed
US-20170291922-A1 DELTA RECEPTOR AGONIST PEPTIDES AND USE THEREOF Ariel Scientific Innovations Ltd. (IL) 2017-10-12 US disclosed
EP-1353701-B1 METHODS FOR PRODUCING COMPOSITIONS FOR ENHANCED DELIVERY OF BIOACTIVE MOLECULES PR PHARMACEUTICALS INC (US) 2011-12-21 EP disclosed
EP-2316490-A2 Methods and compositions for enhanced delivery of bioactive molecules PR Pharmaceuticals, Inc. (US) 2011-05-04 EP disclosed
US-20080292712-A1 METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF BIOACTIVE MOLECULES PR PHARMACEUTICALS, INC. (US) 2008-11-27 US disclosed
US-20040185103-A1 Methods and compositions for enhanced delivery of bioactive molecules BROOKWOOD PHARMACEUTICALS, INC. 2004-09-23 US disclosed
US-6706289-B2 FOR CONTROLLED, PROLONGED RELEASE OF BIOACTIVE MOLECULES SUCH AS THERAPEUTIC PROTEINS, PEPTIDES AND OLIGONUCLEOTIDES PR PHARMACEUTICALS, INC. 2004-03-16 US disclosed
EP-1353701-A2 METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF BIOACTIVE MOLECULES PR Pharmaceuticals, Inc. (US) 2003-10-22 EP disclosed
US-20020155158-A1 Methods and compositions for enhanced delivery of bioactive molecules EVONIK CORPORATION 2002-10-24 US disclosed
WO-2002036169-A2 METHODS AND COMPOSITIONS FOR ENHANCED DELIVERY OF BIOACTIVE MOLECULES PR PHARMACEUTICALS, INC. (US) 2002-05-10 WO disclosed