SCHEMBL1898421

SCHEMBL1898421

CCCCCC(C)Nc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.53
▸ MAPK1 P28482 4/20 0.53
▸ EGFR P00533 3/20 0.53
▸ L3MBTL1 Q9Y468 3/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ TDP1 Q9NUW8 2/20 0.53
▸ PABPC1 P11940 1/20 0.53
▸ RAB9A P51151 1/20 0.53
▸ MAOA P21397 1/20 0.48
▸ ALDH1A1 P00352 3/20 0.43
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ POLB P06746 2/20 0.43
▸ RAD52 P43351 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ DNMT1 P26358 1/20 0.43
▸ SMARCA2 P51531 1/20 0.43
▸ LMNA P02545 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639310 0.84 MAPT (0.60) MAPTMAPK1EGFRL3MBTL1SMN1; SMN2
SCHEMBL11524920 0.80 IDO1 (0.43) MAPK1L3MBTL1KMT2A
SCHEMBL6664912 0.80 MAPT (0.58) MAPTMAPK1EGFRL3MBTL1SMN1; SMN2
SCHEMBL13070793 0.79 SMN1; SMN2 (0.45) MAPTMAPK1EGFRL3MBTL1SMN1; SMN2
SCHEMBL11526271 0.78 ADH1B (0.44) MAPK1L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL11527742 0.78 ADH1B (0.44) MAPK1L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL10597073 0.78 ADH1B (0.44) MAPK1L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL45259 0.78 MEN1 (0.63) MAPTMAPK1EGFRL3MBTL1SMN1; SMN2
SCHEMBL7854850 0.77 MEN1 (0.61) MAPTMAPK1EGFRL3MBTL1SMN1; SMN2
SCHEMBL13587207 0.77 MEN1 (0.61) MAPTMAPK1EGFRL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2013-01-03 — — US claimed
EP-2504103-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M Innovative Properties Company (US) 2012-10-03 — — EP claimed
WO-2011063332-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-26 — — WO claimed
CN-111514950-A System and method for sample concentration and detection using separation fluid 3M创新有限公司 2020-08-11 — — CN disclosed
US-10639629-B2 Systems and methods for sample concentration and detection using a separation liquid 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-05-05 — — US disclosed
US-20200088615-A1 SYSTEMS AND METHODS FOR RAPID DETECTION OF AN ANALYTE OF INTEREST 3M INNOVATIVE PROPERTIES COMPANY 2020-03-19 — — US disclosed
EP-3551991-A1 SYSTEMS AND METHODS FOR RAPID DETECTION OF AN ANALYTE OF INTEREST 3M Innovative Properties Company (US) 2019-10-16 — — EP disclosed
EP-2826564-B1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES CO (US) 2018-12-26 — — EP disclosed
WO-2018106488-A1 SYSTEMS AND METHODS FOR RAPID DETECTION OF AN ANALYTE OF INTEREST 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-06-14 — — WO disclosed
US-9909969-B2 Systems and methods for detecting an analyte of interest in a sample using microstructured surfaces 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-06 — — US disclosed
US-9880102-B2 Microwell array articles and methods of use 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-01-30 — — US disclosed
EP-2726842-B1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M INNOVATIVE PROPERTIES CO (US) 2016-03-16 — — EP disclosed
US-20160025637-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2016-01-28 — — US disclosed
EP-2826564-A1 Microwell array articles and methods of use 3M Innovative Properties Company of 3M Center (US) 2015-01-21 — — EP disclosed
EP-2726842-A1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M Innovative Properties Company (US) 2014-05-07 — — EP disclosed
US-20140096598-A1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-10 — — US disclosed
WO-2013003308-A1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-03 — — WO disclosed
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2013-01-03 — — US disclosed
EP-2504103-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M Innovative Properties Company (US) 2012-10-03 — — EP disclosed
WO-2011063332-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE CD68, ANXA2, ANXA5 MAPT 1788/4885MAPK1 4675/4885EGFR 3185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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