SCHEMBL1898424

SCHEMBL1898424

CCCCCCCNc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.61
KMT2A Q03164 7/20 0.61
MAPT P10636 5/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
L3MBTL1 Q9Y468 4/20 0.61
ALDH1A1 P00352 4/20 0.61
POLB P06746 4/20 0.61
MAPK1 P28482 3/20 0.61
HTT P42858 3/20 0.61
EGFR P00533 2/20 0.61
LMNA P02545 2/20 0.61
RECQL P46063 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
BLM P54132 2/20 0.61
RAD52 P43351 2/20 0.61
TERT O14746 1/20 0.58
NSD2 O96028 2/20 0.56
FGB P02675 1/20 0.56
MMP14 P50281 1/20 0.56
TDP1 Q9NUW8 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7853370 1.00 MEN1 (0.61) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
SCHEMBL13587207 1.00 MEN1 (0.61) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
SCHEMBL7854850 1.00 MEN1 (0.61) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
SCHEMBL45259 0.98 MEN1 (0.63) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
Ammonia Solution, Strong SCHEMBL11423642 0.97 MEN1 (0.61) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
SCHEMBL6372317 0.95 NSD2 (0.60) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
SCHEMBL7855164 0.95 NSD2 (0.60) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
SCHEMBL11872149 0.94 TERT (0.64) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
SCHEMBL6291460 0.94 MEN1 (0.64) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1
SCHEMBL9906063 0.94 TERT (0.64) MEN1KMT2AMAPTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2013-01-03 US claimed
EP-2504103-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M Innovative Properties Company (US) 2012-10-03 EP claimed
WO-2011063332-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-26 WO claimed
CN-111514950-A System and method for sample concentration and detection using separation fluid 3M创新有限公司 2020-08-11 CN disclosed
US-10639629-B2 Systems and methods for sample concentration and detection using a separation liquid 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-05-05 US disclosed
US-20200088615-A1 SYSTEMS AND METHODS FOR RAPID DETECTION OF AN ANALYTE OF INTEREST 3M INNOVATIVE PROPERTIES COMPANY 2020-03-19 US disclosed
EP-2826564-B1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES CO (US) 2018-12-26 EP disclosed
US-9909969-B2 Systems and methods for detecting an analyte of interest in a sample using microstructured surfaces 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-06 US disclosed
US-9880102-B2 Microwell array articles and methods of use 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-01-30 US disclosed
US-20170363545-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES CO (US) 2017-12-21 US disclosed
US-9759663-B2 Microwell array articles and methods of use 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-09-12 US disclosed
US-20160310941-A1 SYSTEMS AND METHODS FOR SAMPLE CONCENTRATION AND DETECTION USING A SEPARATION LIQUID NEOGEN FOOD SAFETY US HOLDCO CORPORATION 2016-10-27 US disclosed
EP-3083055-A1 SYSTEMS AND METHODS FOR SAMPLE CONCENTRATION AND DETECTION USING A SEPARATION LIQUID 3M Innovative Properties Company (US) 2016-10-26 EP disclosed
EP-2726842-B1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M INNOVATIVE PROPERTIES CO (US) 2016-03-16 EP disclosed
US-20160025637-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2016-01-28 US disclosed
EP-2826564-A1 Microwell array articles and methods of use 3M Innovative Properties Company of 3M Center (US) 2015-01-21 EP disclosed
US-20140096598-A1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-10 US disclosed
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2013-01-03 US disclosed
EP-2504103-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M Innovative Properties Company (US) 2012-10-03 EP disclosed
WO-2011063332-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE CD68, ANXA2, ANXA5 MEN1 3326/4885KMT2A 4489/4885MAPT 1788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.