⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2282237 | 0.82 | — | — | |
| SCHEMBL3541977 | 0.75 | — | — | |
| SCHEMBL56455 | 0.73 | — | — | |
| SCHEMBL4057839 | 0.73 | — | — | |
| SCHEMBL55857 | 0.73 | — | — | |
| SCHEMBL9574541 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL5733536 | 0.71 | — | — | |
| SCHEMBL6948350 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL1191245 | 0.69 | — | — | |
| SCHEMBL4750924 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324809-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS AND USES THEREOF | SALZMAN GROUP LTD (IL) | 2022-10-13 | — | — | US | disclosed |
| EP-4025300-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS COMPRISING GUANIDINE AND USES THEREOF | Salzman Group Ltd. (IL) | 2022-07-13 | — | — | EP | disclosed |
| WO-2021044413-A1 | ATP-REGULATED POTASSIUM CHANNEL OPENERS COMPRISING GUANIDINE AND USES THEREOF | SALZMAN GROUP LTD. (IL) | 2021-03-11 | — | — | WO | disclosed |
| US-9085786-B2 | Process for the production of polyamines | BASF SE (DE) | 2015-07-21 | — | — | US | disclosed |
| EP-2510104-A2 | PROCESS FOR PRODUCING POLYAMINES COMPRISING THE ENZYMATIC OXIDATION OF AMINO ALCOHOLS | BASF SE (DE) | 2012-10-17 | — | — | EP | disclosed |
| US-20120225932-A1 | PROCESS FOR THE PRODUCTION OF POLYAMINES | BASF SE (DE) | 2012-09-06 | — | — | US | disclosed |
| WO-2011051433-A2 | PROCESS FOR THE PRODUCTION OF POLYAMINES | BASF SE (DE) | 2011-05-05 | — | — | WO | disclosed |