Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 7/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955773 | 0.76 | — | — | |
| SCHEMBL25475495 | 0.68 | CSF1R (0.35) | CD38CSF1RKMT2A | |
| SCHEMBL1379743 | 0.68 | GAA (0.50) | TGM2LMNAKMT2A | |
| SCHEMBL1553945 | 0.67 | — | — | |
| SCHEMBL21585659 | 0.67 | TGM2 (0.55) | TGM2F13A1LMNATGM1TGM3 | |
| Bicarbonate SCHEMBL28121604 | 0.67 | KMT2A (0.34) | CD38CSF1RKMT2A | |
| SCHEMBL6235734 | 0.67 | — | — | |
| SCHEMBL11997717 | 0.67 | KMT2A (0.50) | KMT2A | |
| SCHEMBL31536297 | 0.67 | KMT2A (0.50) | KMT2A | |
| SCHEMBL6424749 | 0.67 | NPC1 (0.54) | GSTO1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |