Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 20/20 | 0.82 |
| ▸ | FLT3 | P36888 | 2/20 | 0.62 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.58 |
| ▸ | CDK9 | P50750 | 1/20 | 0.58 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985231 | 0.90 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL18985202 | 0.90 | TBK1 (1.00) | TBK1FLT3IKBKECCNT1CDK9 | |
| SCHEMBL19005045 | 0.89 | TBK1 (0.73) | TBK1FLT3IKBKE | |
| Hydrochloric Acid SCHEMBL20721077 | 0.88 | TBK1 (0.72) | TBK1FLT3IKBKE | |
| SCHEMBL18985540 | 0.79 | TBK1 (1.00) | TBK1FLT3IKBKE | |
| SCHEMBL18986128 | 0.78 | TBK1 (0.84) | TBK1 | |
| SCHEMBL18985947 | 0.77 | TBK1 (0.65) | TBK1IKBKECCNT1CDK9 | |
| SCHEMBL18985589 | 0.77 | TBK1 (1.00) | TBK1 | |
| SCHEMBL18986007 | 0.77 | TBK1 (0.84) | TBK1 | |
| SCHEMBL18985879 | 0.77 | TBK1 (1.00) | TBK1FLT3IKBKECCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390387-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |