Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23648 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL28215144 | 0.87 | FOLH1 (0.52) | FOLH1GRM8GRM6GRM7GRM4 | |
| Water SCHEMBL28860761 | 0.87 | FOLH1 (0.52) | FOLH1GRM8GRM6GRM7GRM4 | |
| SCHEMBL11089864 | 0.87 | FOLH1 (0.52) | FOLH1GRM8GRM6GRM7GRM4 | |
| Hydrochloric Acid SCHEMBL28145400 | 0.87 | FOLH1 (0.52) | FOLH1GRM8GRM6GRM7GRM4 | |
| Butane SCHEMBL7716762 | 0.85 | FFAR3 (0.50) | FOLH1TDP1MEN1TSHRKMT2A | |
| Benzene SCHEMBL28265143 | 0.84 | FOLH1 (0.50) | FOLH1GRM8GRM6GRM7GRM4 | |
| SCHEMBL28696904 | 0.79 | ALDH1A1 (0.43) | FOLH1GRM8GRM6GRM7GRM4 | |
| Hexane SCHEMBL27503551 | 0.79 | LPAR3 (0.58) | TDP1MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL2290779 | 0.78 | CTSC (0.49) | FOLH1GRM8GRM6GRM7GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100849-A1 | 6-OXOPURINE PHOSPHORIBOSYL TRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-06-22 | — | — | WO | disclosed |