Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985633 | 0.96 | TBK1 (0.76) | TBK1 | |
| SCHEMBL18986187 | 0.86 | TBK1 (0.75) | TBK1 | |
| SCHEMBL18985798 | 0.86 | TBK1 (0.73) | TBK1 | |
| SCHEMBL19003994 | 0.86 | TBK1 (1.00) | TBK1 | |
| SCHEMBL18985708 | 0.83 | TBK1 (0.75) | TBK1 | |
| SCHEMBL18985776 | 0.83 | TBK1 (0.76) | TBK1 | |
| SCHEMBL19005199 | 0.82 | TBK1 (1.00) | TBK1 | |
| SCHEMBL18985888 | 0.81 | TBK1 (0.74) | TBK1 | |
| SCHEMBL18985742 | 0.79 | TBK1 (0.75) | TBK1 | |
| SCHEMBL19005235 | 0.78 | TBK1 (1.00) | TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390387-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-24 | — | — | EP | claimed |
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | claimed |
| EP-3390387-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |