Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | KMO | O15229 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8255870 | 0.81 | ASIC3 (0.53) | ASIC3MIFKMONPC1RAB9A | |
| SCHEMBL284286 | 0.79 | ASIC3 (0.71) | ASIC3MIFKMONPC1RAB9A | |
| SCHEMBL28218682 | 0.77 | ASIC3 (0.68) | ASIC3MIFKMONPC1RAB9A | |
| SCHEMBL27904874 | 0.77 | ASIC3 (0.68) | ASIC3MIFKMONPC1RAB9A | |
| SCHEMBL29406194 | 0.77 | ASIC3 (0.68) | ASIC3MIFKMONPC1RAB9A | |
| SCHEMBL18985795 | 0.75 | KMT2A (0.42) | ASIC3KMOKMT2AKDM4EALDH1A1 | |
| SCHEMBL18731738 | 0.74 | ASIC3 (0.65) | ASIC3MIFKMONPC1RAB9A | |
| SCHEMBL29730373 | 0.74 | ASIC3 (0.65) | ASIC3MIFKMONPC1RAB9A | |
| SCHEMBL17697185 | 0.74 | ASIC3 (0.65) | ASIC3MIFKMONPC1RAB9A | |
| SCHEMBL4150983 | 0.73 | ASIC3 (0.49) | ASIC3MIFKMONPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390387-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |