Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247781 | 0.91 | CA1 (0.39) | CA1CA2MAPTLMNAALDH1A1 | |
| SCHEMBL8922405 | 0.88 | CA1 (0.40) | CA1CA2MAPTLMNAALDH1A1 | |
| SCHEMBL8441278 | 0.87 | CA1 (0.39) | CA1CA2MAPTLMNAALDH1A1 | |
| SCHEMBL13021504 | 0.85 | MAOB (0.46) | CA1CA2MAPTLMNAESRRA | |
| SCHEMBL2801917 | 0.84 | CA1 (0.34) | CA1CA2MAPTLMNAALDH1A1 | |
| SCHEMBL13021503 | 0.83 | CA1 (0.43) | CA1CA2MAPTLMNAALDH1A1 | |
| SCHEMBL9620532 | 0.83 | CA1 (0.42) | CA1CA2MAPTLMNAALDH1A1 | |
| SCHEMBL24205703 | 0.82 | CA1 (0.42) | CA1CA2MAPTLMNAALDH1A1 | |
| SCHEMBL2778858 | 0.82 | POLB (0.35) | CA1CA2MAPTLMNAALDH1A1 | |
| SCHEMBL29399534 | 0.82 | POLB (0.35) | CA1CA2MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | claimed |
| EP-3958788-A1 | SYSTEM AND METHOD | Merck Patent GmbH (DE) | 2022-03-02 | — | — | EP | disclosed |
| WO-2020216928-A1 | SYSTEM AND METHOD | MERCK PATENT GMBH (DE) | 2020-10-29 | — | — | WO | disclosed |
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |
| EP-3391100-A1 | AMPHIPHILIC BRANCHED POLYDIORGANOSILOXANE MACROMERS | Novartis AG (CH) | 2018-10-24 | — | — | EP | disclosed |
| WO-2017103792-A1 | AMPHIPHILIC BRANCHED POLYDIORGANOSILOXANE MACROMERS | NOVARTIS AG (CH) | 2017-06-22 | — | — | WO | disclosed |