Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441278 | 0.96 | CA1 (0.39) | CA1CA2ACSS2MAPTLMNA | |
| SCHEMBL9512829 | 0.86 | CA1 (0.37) | CA1CA2MAPTLMNATP53 | |
| SCHEMBL23638712 | 0.86 | NPC1 (0.37) | CA1CA2ACSS2MAPTLMNA | |
| SCHEMBL8922405 | 0.86 | CA1 (0.40) | CA1CA2MAPTLMNANPC1 | |
| SCHEMBL30887134 | 0.86 | CA1 (0.38) | CA1CA2LMNATP53PDE3B | |
| SCHEMBL21586965 | 0.85 | NPC1 (0.40) | CA1CA2ACSS2MAPTLMNA | |
| SCHEMBL30887157 | 0.85 | PDE2A (0.36) | CA1CA2ACSS2MAPTLMNA | |
| SCHEMBL21586947 | 0.85 | PDE2A (0.36) | CA1CA2ACSS2MAPTLMNA | |
| SCHEMBL1247781 | 0.85 | CA1 (0.39) | CA1CA2MAPTLMNATP53 | |
| SCHEMBL3879963 | 0.84 | POLB (0.39) | CA1CA2MAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283166-B1 | 2-(2'-HYDROXYPHENYL)-5(6) (ACRYLOYLOXYALKOXY)-BENZOTRIAZOLE AND ULTRAVIOLET ABSORBING POLYMERS THEREFROM | IOLAB CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |