Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18988624 | 0.93 | PIK3CD (0.47) | PIK3CDPIK3CADPP4PIK3CBPIK3CG | |
| SCHEMBL19006156 | 0.91 | PIK3CD (0.45) | PIK3CDPIK3CAPTGS1PTGS2DPP4 | |
| SCHEMBL18988459 | 0.89 | PIK3CD (0.40) | PIK3CDPIK3CA | |
| SCHEMBL19006161 | 0.84 | PIK3CD (0.48) | PIK3CDPIK3CADPP4PIK3CBPIK3CG | |
| SCHEMBL18989298 | 0.80 | PIK3CD (0.43) | PIK3CDPIK3CADPP4MAOBPIK3CB | |
| SCHEMBL19006273 | 0.80 | PIK3CD (0.41) | PIK3CDPIK3CADPP4 | |
| SCHEMBL19006155 | 0.77 | PIK3CD (0.52) | PIK3CDPIK3CAPTGS1PTGS2DPP4 | |
| SCHEMBL18988617 | 0.76 | PIK3CD (0.65) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988519 | 0.74 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006249 | 0.73 | PIK3CD (0.67) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |