Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 12/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18988624 | 0.91 | PIK3CD (0.47) | PIK3CDPIK3CAFABP4PIK3CBPIK3CG | |
| SCHEMBL19006273 | 0.91 | PIK3CD (0.41) | PIK3CDPIK3CAFABP4CYP11B1CYP11B2 | |
| SCHEMBL18988560 | 0.84 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL18988459 | 0.82 | PIK3CD (0.40) | PIK3CDPIK3CA | |
| SCHEMBL19006315 | 0.81 | PIK3CD (0.46) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL19006159 | 0.80 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBPIK3CGCYP11B1 | |
| SCHEMBL18989298 | 0.75 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 | |
| SCHEMBL18988694 | 0.74 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006198 | 0.74 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988763 | 0.74 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |