SCHEMBL18988945

SCHEMBL18988945

CCS(=O)(=O)c1cc(C(F)(F)F)ccc1-c1ncc(C=O)n1C

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 8/20 0.39
FEN1 P39748 8/20 0.39
DDR1 Q08345 8/20 0.39
PTGDR2 Q9Y5Y4 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29755613 1.00 ALOX5AP (0.39) ALOX5APFEN1DDR1PTGDR2
SCHEMBL20544075 0.88 PTGDR2 (0.37) ALOX5APFEN1DDR1PTGDR2
SCHEMBL20544074 0.88 PTGDR2 (0.37) ALOX5APFEN1DDR1PTGDR2
SCHEMBL29755480 0.86 PTGDR2 (0.36) ALOX5APFEN1DDR1PTGDR2
SCHEMBL18989151 0.86 PTGDR2 (0.36) ALOX5APFEN1DDR1PTGDR2
SCHEMBL18989152 0.86 PTGDR2 (0.36) ALOX5APFEN1DDR1PTGDR2
SCHEMBL24208925 0.85 DDR1 (0.36) ALOX5APFEN1DDR1PTGDR2
SCHEMBL20544185 0.85 DDR1 (0.38) ALOX5APFEN1DDR1PTGDR2
SCHEMBL20544078 0.85 DDR1 (0.38) ALOX5APFEN1DDR1PTGDR2
SCHEMBL19017507 0.85 DDR1 (0.41) ALOX5APFEN1DDR1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4029856-B1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2024-03-27 EP disclosed
US-11884633-B2 Arylazole compound and pest control agent NIPPON SODA CO., LTD. (JP) 2024-01-30 US disclosed
CN-115181067-A Arylpyrazole compound and pest control agent 日本曹达株式会社 2022-10-14 CN disclosed
EP-4029856-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2022-07-20 EP disclosed
CN-108430976-B Arylpyrazole compound and pest control agent 日本曹达株式会社 2022-07-05 CN disclosed
US-20220017472-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2022-01-20 US disclosed
US-20220017472-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2022-01-20 US disclosed
US-11180456-B2 Arylazole compound and pest control agent NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
US-11180456-B2 Arylazole compound and pest control agent NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
EP-3395801-B1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2021-03-31 EP disclosed
EP-3395801-B1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2021-03-31 EP disclosed
US-20180362470-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2018-12-20 US disclosed
EP-3395801-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2018-10-31 EP disclosed
WO-2017104741-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT 日本曹達株式会社 2017-06-22 WO disclosed
WO-2017104741-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT 日本曹達株式会社 2017-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180362470-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT DDT, CYP4B1, NAT1 ALOX5AP 2010/4885FEN1 2886/4885DDR1 2093/4885
US-11180456-B2 Arylazole compound and pest control agent DDT, CYP4B1, NAT1 ALOX5AP 2010/4885FEN1 2886/4885DDR1 2093/4885
US-20220017472-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT DDT, CYP4B1, NAT1 ALOX5AP 2010/4885FEN1 2886/4885DDR1 2093/4885
US-11884633-B2 Arylazole compound and pest control agent DDT, CYP4B1, NAT1 ALOX5AP 2010/4885FEN1 2886/4885DDR1 2093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.