SCHEMBL20544185

SCHEMBL20544185

CCS(=O)(=O)c1cc(C(F)(F)F)ccc1-c1ncc(/C=C(\Cl)C(F)(F)F)n1C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 8/20 0.38
ALOX5AP P20292 6/20 0.37
FEN1 P39748 6/20 0.37
PTGDR2 Q9Y5Y4 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20544078 1.00 DDR1 (0.38) DDR1ALOX5APFEN1PTGDR2
SCHEMBL18989169 0.92 DDR1 (0.37) DDR1ALOX5APFEN1PTGDR2
SCHEMBL29755430 0.92 DDR1 (0.37) DDR1ALOX5APFEN1PTGDR2
SCHEMBL18989167 0.92 DDR1 (0.37) DDR1ALOX5APFEN1PTGDR2
SCHEMBL24208923 0.85 DDR1 (0.36) DDR1ALOX5APFEN1PTGDR2
SCHEMBL18988945 0.85 ALOX5AP (0.39) DDR1ALOX5APFEN1PTGDR2
SCHEMBL29755613 0.85 ALOX5AP (0.39) DDR1ALOX5APFEN1PTGDR2
SCHEMBL20544074 0.82 PTGDR2 (0.37) DDR1ALOX5APFEN1PTGDR2
SCHEMBL20544075 0.82 PTGDR2 (0.37) DDR1ALOX5APFEN1PTGDR2
SCHEMBL18989151 0.80 PTGDR2 (0.36) DDR1ALOX5APFEN1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4029856-B1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2024-03-27 EP disclosed
US-11884633-B2 Arylazole compound and pest control agent NIPPON SODA CO., LTD. (JP) 2024-01-30 US disclosed
EP-4029856-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2022-07-20 EP disclosed
US-20220017472-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2022-01-20 US disclosed
US-20210380554-A1 (HETERO)ARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2021-12-09 US disclosed
US-11180456-B2 Arylazole compound and pest control agent NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
EP-3395801-B1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2021-03-31 EP disclosed
US-20180362470-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2018-12-20 US disclosed
EP-3395801-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2018-10-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180362470-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT DDT, CYP4B1, NAT1 DDR1 2093/4885ALOX5AP 2010/4885FEN1 2886/4885
US-11180456-B2 Arylazole compound and pest control agent DDT, CYP4B1, NAT1 DDR1 2093/4885ALOX5AP 2010/4885FEN1 2886/4885
US-20220017472-A1 ARYLAZOLE COMPOUND AND PEST CONTROL AGENT DDT, CYP4B1, NAT1 DDR1 2093/4885ALOX5AP 2010/4885FEN1 2886/4885
US-11884633-B2 Arylazole compound and pest control agent DDT, CYP4B1, NAT1 DDR1 2093/4885ALOX5AP 2010/4885FEN1 2886/4885
US-20210380554-A1 (HETERO)ARYLIMIDAZOLE COMPOUND AND HARMFUL ORGANISM CONTROL AGENT NAT1, CTRL, CYP8B1 DDR1 4851/4885ALOX5AP 4151/4885FEN1 2991/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.