Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | P4HA1 | P13674 | 3/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.45 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.45 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.45 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.45 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14376760 | 0.86 | KCNJ1 (0.66) | LMNAKCNJ1EGLN1TET2OGFOD1 | |
| SCHEMBL15653755 | 0.82 | KCNJ1 (0.43) | LMNAKCNJ1EGLN1TET2OGFOD1 | |
| SCHEMBL2570669 | 0.79 | EGLN2 (0.72) | LMNAP4HTMEGLN1TET2OGFOD1 | |
| SCHEMBL14921306 | 0.79 | KCNJ1 (0.74) | LMNAKCNJ1P4HA1P4HTMEGLN1 | |
| Hydrochloric Acid SCHEMBL3706626 | 0.79 | EGLN2 (0.71) | LMNAP4HTMEGLN1TET2OGFOD1 | |
| SCHEMBL322839 | 0.77 | LMNA (1.00) | LMNAP4HA1P4HTMEGLN1MIF | |
| SCHEMBL29425707 | 0.77 | LMNA (1.00) | LMNAP4HA1P4HTMEGLN1MIF | |
| SCHEMBL19277438 | 0.76 | NOTUM (0.39) | LMNAKCNJ1EGLN1TET2OGFOD1 | |
| SCHEMBL462839 | 0.76 | NOTUM (0.56) | KCNJ1KMT2ANAPRTALDH1A1HPGD | |
| SCHEMBL14822076 | 0.73 | LMNA (0.57) | LMNAKCNJ1P4HA1P4HTMEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |