Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10289438 | 0.77 | ALDH1A1 (0.39) | PTGS1ALDH1A1CNR1CNR2TRPA1 | |
| SCHEMBL10535096 | 0.77 | ALDH1A1 (0.39) | PTGS1ALDH1A1CNR1CNR2TRPA1 | |
| SCHEMBL25732848 | 0.76 | ALDH1A1 (0.32) | PTGS1ALDH1A1 | |
| SCHEMBL19152232 | 0.75 | PTGS1 (0.58) | PTGS1ALDH1A1 | |
| SCHEMBL14953173 | 0.75 | PTGS1 (0.58) | PTGS1ALDH1A1 | |
| SCHEMBL14953172 | 0.75 | PTGS1 (0.58) | PTGS1ALDH1A1 | |
| SCHEMBL17752195 | 0.73 | — | — | |
| SCHEMBL15081571 | 0.73 | — | — | |
| SCHEMBL15081470 | 0.73 | — | — | |
| SCHEMBL20754284 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682097-B2 | Oligonucleotide analogues targeting human LMNA | SAREPTA THERAPEUTICS, INC. (US) | 2017-06-20 | — | — | US | disclosed |