Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 6/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15495793 | 0.87 | ELANE (0.50) | KIF11ELANEMAOBALDH1A1CYP1A1 | |
| SCHEMBL15279326 | 0.82 | ELANE (0.56) | ELANEALDH1A1 | |
| SCHEMBL12727386 | 0.82 | KIF11 (0.56) | KIF11ELANEMAOBALDH1A1CYP11B1 | |
| SCHEMBL18994832 | 0.82 | ELANE (0.66) | KIF11ELANEMAOBCYP11B1CYP11B2 | |
| SCHEMBL15241694 | 0.80 | ELANE (0.37) | KIF11ELANEPPARAPPARD | |
| SCHEMBL12691185 | 0.79 | ELANE (0.56) | KIF11ELANEMAOBALDH1A1PRSS1 | |
| SCHEMBL539078 | 0.79 | ELANE (0.50) | ELANE | |
| SCHEMBL14434694 | 0.78 | ELANE (0.41) | ELANEALDH1A1PPARA | |
| SCHEMBL26215686 | 0.78 | ELANE (0.59) | ELANEALDH1A1 | |
| SCHEMBL22238731 | 0.78 | ELANE (0.51) | ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682962-B2 | Pyrazolyl pyrimidinamine compound and application thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-06-20 | — | — | US | disclosed |