Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.58 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 3/20 | 0.47 |
| ▸ | MC4R | P32245 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
| ▸ | ITGAL | P20701 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15685572 | 0.96 | SLC15A2 (0.62) | SLC15A2SLC6A5RENMC4RACE2 | |
| SCHEMBL15683029 | 0.95 | SLC15A2 (0.63) | SLC15A2SLC6A5RENMC4RACE2 | |
| SCHEMBL15685547 | 0.87 | SLC15A2 (0.55) | SLC15A2RENMC4RACE2EPHX2 | |
| SCHEMBL15683028 | 0.85 | SLC15A2 (0.49) | SLC15A2SIRT6SIRT1RENMC4R | |
| SCHEMBL15683034 | 0.85 | SLC15A2 (0.52) | SLC15A2SLC6A5RENMC4RACE2 | |
| SCHEMBL15683026 | 0.80 | SLC15A2 (0.47) | SLC15A2RENMC4R | |
| SCHEMBL15683050 | 0.79 | MC4R (0.48) | SLC15A2RENMC4R | |
| SCHEMBL15683044 | 0.77 | ITGB2 (0.64) | SLC15A2SLC6A5RENACE2ITGB2 | |
| SCHEMBL468830 | 0.77 | ITGB2 (0.64) | SLC15A2SLC6A5RENACE2ITGB2 | |
| SCHEMBL6026427 | 0.77 | ITGB2 (0.64) | SLC15A2SLC6A5RENACE2ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682157-B2 | PH-sensitive imaging agents | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2017-06-20 | — | — | US | disclosed |