Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 4/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18994920 | 0.90 | CA1 (0.41) | MC4RCA1CA2NLN | |
| SCHEMBL15683050 | 0.88 | MC4R (0.48) | SLC15A2MC4RREN | |
| SCHEMBL15685572 | 0.83 | SLC15A2 (0.62) | SLC15A2MC4RREN | |
| SCHEMBL15683029 | 0.82 | SLC15A2 (0.63) | SLC15A2MC4RREN | |
| SCHEMBL18994919 | 0.82 | REN (0.41) | SLC15A2MC4RREN | |
| SCHEMBL18994930 | 0.80 | SLC15A2 (0.58) | SLC15A2MC4RREN | |
| SCHEMBL15683028 | 0.79 | SLC15A2 (0.49) | SLC15A2MC4RREN | |
| SCHEMBL15685547 | 0.76 | SLC15A2 (0.55) | SLC15A2MC4RREN | |
| SCHEMBL27550844 | 0.74 | DRD1 (0.65) | CA1CA2 | |
| SCHEMBL11339783 | 0.74 | DRD1 (0.65) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682157-B2 | PH-sensitive imaging agents | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2017-06-20 | — | — | US | disclosed |
| US-9682157-B2 | PH-sensitive imaging agents | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2017-06-20 | — | — | US | disclosed |
| US-20140127138-A1 | PH-SENSITIVE IMAGING AGENTS | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
| US-20140127138-A1 | PH-SENSITIVE IMAGING AGENTS | BOARD OF TRUSTEES OF SOUTHERN ILLINOIS UNIVERSITY (US) | 2014-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127138-A1 | PH-SENSITIVE IMAGING AGENTS | PHF6, PHF13, SLC11A2 | SLC15A2 2398/4885MC4R 4685/4885REN 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.