Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569282 | 0.83 | NCF1 (0.46) | NCF1KDM1AMAOBHRH3HRH4 | |
| SCHEMBL18822911 | 0.74 | NCF1 (0.50) | NCF1KDM1AMAOBHRH3HRH4 | |
| SCHEMBL12665755 | 0.73 | NCF1 (0.40) | NCF1KDM1AMAOBHRH3HRH4 | |
| SCHEMBL1488427 | 0.72 | NCF1 (0.52) | NCF1KDM1AMAOBHRH3HRH4 | |
| SCHEMBL24688742 | 0.71 | NCF1 (0.42) | NCF1KDM1AMAOBHRH3NSD2 | |
| SCHEMBL24319800 | 0.70 | NCF1 (0.62) | NCF1KDM1AMAOBHRH3HRH4 | |
| SCHEMBL16246818 | 0.70 | NCF1 (0.56) | NCF1KDM1AMAOBHRH3HRH4 | |
| SCHEMBL1488424 | 0.70 | NCF1 (0.50) | NCF1KDM1AMAOBHRH3HRH4 | |
| SCHEMBL17886879 | 0.69 | NCF1 (0.45) | NCF1KDM1AMAOBHRH3HRH4 | |
| SCHEMBL12935918 | 0.69 | CKS1B (0.45) | NCF1HDAC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682141-B2 | Combination of kinase inhibitors and uses thereof | INTELLIKINE LLC (US) | 2017-06-20 | — | — | US | disclosed |