Succinic Acid

Succinic Acid

SCHEMBL1899650

O=C(O)CCC(=O)O.OCCCCCCO

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4

The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.46
GPR84 Q9NQS5 7/20 0.82
FFAR1 O14842 2/20 0.82
FFAR4 Q5NUL3 2/20 0.82
CAMK2A Q9UQM7 1/20 0.71
LMNA P02545 4/20 0.60
ALKBH5 Q6P6C2 1/20 0.60
SUCNR1 Q9BXA5 1/20 0.60
EGLN1 Q9GZT9 1/20 0.60
TSHR P16473 5/20 0.59
NFKB1 P19838 1/20 0.59
PMP22 Q01453 1/20 0.59
SLC22A6 Q4U2R8 2/20 0.53
FNTA P49354 1/20 0.52
FNTB P49356 1/20 0.52
PPARG P37231 6/20 0.46
PPARD Q03181 6/20 0.46
PPARA Q07869 6/20 0.46
HDAC11 Q96DB2 5/20 0.46
ALDH1A1 P00352 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL29958676 1.00 GPR84 (0.82) GPR84FFAR1FFAR4CAMK2ALMNA
Succinic Acid SCHEMBL27941090 1.00 GPR84 (0.82) GPR84FFAR1FFAR4CAMK2ALMNA
Succinic Acid SCHEMBL27855292 1.00 GPR84 (0.82) GPR84FFAR1FFAR4CAMK2ALMNA
Succinic Acid SCHEMBL30254944 0.97 GPR84 (0.77) GPR84FFAR1FFAR4CAMK2ALMNA
Succinic Acid SCHEMBL1132170 0.97 GPR84 (0.77) GPR84FFAR1FFAR4CAMK2ALMNA
Sebacic Acid SCHEMBL28902911 0.94 GPR84 (0.94) GPR84FFAR1FFAR4CAMK2ALMNA
Succinic Acid SCHEMBL28911181 0.93 GPR84 (0.72) GPR84FFAR1FFAR4CAMK2ALMNA
Adipic Acid SCHEMBL28487639 0.90 GPR84 (0.88) GPR84FFAR1FFAR4CAMK2ALMNA
Adipic Acid SCHEMBL7612785 0.90 GPR84 (0.88) GPR84FFAR1FFAR4CAMK2ALMNA
Succinic Acid SCHEMBL27940383 0.90 GPR84 (0.88) GPR84FFAR1FFAR4CAMK2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116376186-A Antibacterial and anti-aging PVC color master batch and preparation method thereof 广东银豪塑胶制品有限公司 2023-07-04 CN claimed
CN-115260542-A Preparation method of degradable polymer/starch masterbatch 湖北宜化降解新材料有限公司 2022-11-01 CN claimed
CN-115124827-A Preparation method of degradable polymer/calcium carbonate master batch 三峡大学 2022-09-30 CN claimed
CN-114835994-A Ultra-dispersed color master batch and preparation method thereof 南通市金丝利新材料科技有限公司 2022-08-02 CN claimed
CN-107760014-B Solvent-resistant thermoplastic polyurethane elastomer and preparation method thereof 山东一诺威聚氨酯股份有限公司 2021-03-26 CN claimed
CN-108102041-B Carbon nano tube dispersant and preparation method thereof 瑞固新能(上海)材料科技有限公司 2020-10-16 CN claimed
CN-110903574-A PVC environmental protection color master batch 桐乡乐维新材料有限公司 2020-03-24 CN claimed
EP-3356455-A1 HIGH PERFORMANCE COATINGS Resinate Materials Group, Inc. (US) 2018-08-08 EP claimed
CN-108102041-A A kind of Carbon nano-tube dispersant and preparation method thereof 上海三瑞高分子材料股份有限公司 2018-06-01 CN claimed
CN-102443316-A Curable phase change inks containing crystalline polyesters XEROX CORP 2012-05-09 CN claimed
EP-4555025-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-05-13 EP disclosed
EP-3902878-B1 PHOTOINITIATORS IGM RESINS ITALIA SRL (IT) 2026-05-06 EP disclosed
EP-4534614-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-04-15 EP disclosed
EP-4722303-A1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM Group B.V. (NL) 2026-04-08 EP disclosed
EP-4273200-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-03-25 EP disclosed
US-6593434-B1 Condensation polymerization, esterification, melt mixing or kneading; high molecular weight, low crystallinity DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-07-15 US disclosed
CN-1092201-C Alkylphenylbisacylphosphine oxides and photoinitiator mixtures CIBA SC HOLDING AG (CH) 2002-10-09 CN disclosed
EP-1120432-A1 PROCESS FOR THE PRODUCTION OF POLYESTER BLOCK COPOLYMERS, POLYESTER BLOCK COPOLYMER COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-08-01 EP disclosed
CN-1160718-A Alkylphenylbisacylphosphine oxides and photoinitiator mixtures CIBA GEIGY AG (CH) 1997-10-01 CN disclosed
US-5502121-A VISUAL CLARITY FOR COATINGS AND MOLDINGS EASTMAN CHEMICAL COMPANY (US) 1996-03-26 US disclosed