Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | GPR6 | P46095 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769032 | 0.87 | GPR119 (0.65) | GPR119CYP2C9GPR6 | |
| SCHEMBL5046636 | 0.82 | GPR119 (0.59) | GPR119CYP2C9GPR6 | |
| SCHEMBL5188918 | 0.81 | GPR119 (0.64) | GPR119CYP2C9GPR6 | |
| SCHEMBL2786447 | 0.81 | GPR119 (0.79) | GPR119CYP2C9 | |
| SCHEMBL391238 | 0.80 | GPR119 (0.63) | GPR119CYP2C9 | |
| SCHEMBL388992 | 0.79 | GPR119 (0.74) | GPR119CYP2C9 | |
| SCHEMBL388993 | 0.79 | GPR119 (0.74) | GPR119CYP2C9 | |
| SCHEMBL389216 | 0.79 | GPR119 (0.74) | GPR119CYP2C9 | |
| SCHEMBL6440077 | 0.79 | GPR119 (0.71) | GPR119CYP2C9 | |
| SCHEMBL2403601 | 0.79 | GPR119 (0.68) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322152-A1 | Method of preparing a composition comprising a GPR119 agonist | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| EP-1997484-A2 | Method of identifying GLP-1 secretagogues | Arena Pharmaceuticals, Inc. (US) | 2008-12-03 | — | — | EP | disclosed |