Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXM1 | Q08050 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | CRHBP | P24387 | 2/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707114 | 0.91 | FOXM1 (0.81) | FOXM1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL429729 | 0.90 | FOXM1 (0.85) | FOXM1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL18999966 | 0.84 | MAPT (0.62) | FOXM1KMT2AMAPTPOLBMEN1 | |
| SCHEMBL23009467 | 0.83 | KMT2A (0.73) | FOXM1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL14955051 | 0.83 | KMT2A (0.76) | FOXM1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL19769226 | 0.82 | KMT2A (0.74) | FOXM1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL426216 | 0.82 | KMT2A (0.79) | FOXM1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL15919103 | 0.81 | MAPT (0.75) | FOXM1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL13186379 | 0.81 | KMT2A (0.63) | FOXM1KMT2AMAPTPOLBRXFP1 | |
| SCHEMBL29707105 | 0.81 | FOXM1 (1.00) | FOXM1KMT2AMAPTPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181568-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | Siga Technologies, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |