Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.75 |
| ▸ | USP2 | O75604 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | CASP1 | P29466 | 2/20 | 0.75 |
| ▸ | CASP7 | P55210 | 2/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.75 |
| ▸ | RAB9A | P51151 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | FOXM1 | Q08050 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18999965 | 0.81 | FOXM1 (0.68) | MAPTALDH1A1NPSR1USP2SMN1; SMN2 | |
| SCHEMBL429729 | 0.81 | FOXM1 (0.85) | MAPTALDH1A1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL23009467 | 0.80 | KMT2A (0.73) | MAPTALDH1A1SMN1; SMN2CASP1CASP7 | |
| SCHEMBL14955051 | 0.80 | KMT2A (0.76) | MAPTALDH1A1SMN1; SMN2CASP1CASP7 | |
| SCHEMBL18805545 | 0.80 | KMT2A (0.62) | MAPTALDH1A1NPSR1USP2SMN1; SMN2 | |
| SCHEMBL19769226 | 0.79 | KMT2A (0.74) | MAPTALDH1A1CASP1CASP7NPC1 | |
| SCHEMBL426216 | 0.79 | KMT2A (0.79) | MAPTALDH1A1NPSR1USP2SMN1; SMN2 | |
| SCHEMBL430632 | 0.79 | KMT2A (0.64) | MAPTALDH1A1NPSR1USP2SMN1; SMN2 | |
| SCHEMBL13186379 | 0.78 | KMT2A (0.63) | MAPTALDH1A1NPSR1USP2SMN1; SMN2 | |
| SCHEMBL4892272 | 0.76 | LMNA (0.73) | MAPTALDH1A1NPSR1USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160074373-A1 | METHODS AND COMPOSITIONS FOR INHIBITING HUMAN COPPER TRAFFICKING PROTEINS ATOX1 AND CCS | THE UNIVERSITY OF CHICAGO (US) | 2016-03-17 | — | — | US | disclosed |
| WO-2014116859-A1 | METHODS AND COMPOSITIONS FOR INHIBITING HUMAN COPPER TRAFFICKING PROTEINS ATOX1 AND CCS | THE UNIVERSITY OF CHICAGO (US) | 2014-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074373-A1 | METHODS AND COMPOSITIONS FOR INHIBITING HUMAN COPPER TRAFFICKING PROTEINS ATOX1 AND CCS | CLINT1, QSOX1, ACOX1 | MAPT 3330/4885ALDH1A1 725/4885NPSR1 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.