Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.58 |
| ▸ | TP53 | P04637 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18999961 | 0.91 | TDP1 (0.61) | MAPTTP53SMN1; SMN2POLBRXFP1 | |
| SCHEMBL19000241 | 0.89 | MAPT (0.62) | MAPTTP53SMN1; SMN2POLBRXFP1 | |
| SCHEMBL18999971 | 0.89 | MAPT (0.61) | MAPTTP53SMN1; SMN2POLBRXFP1 | |
| SCHEMBL18537653 | 0.88 | ADORA2A (0.68) | MAPTTP53SMN1; SMN2POLBRXFP1 | |
| SCHEMBL18999962 | 0.88 | MAPT (0.64) | MAPTTP53SMN1; SMN2POLBRXFP1 | |
| SCHEMBL18537663 | 0.83 | ALDH1A1 (0.67) | MAPTTP53SMN1; SMN2POLBRXFP1 | |
| SCHEMBL18999842 | 0.83 | MAPT (0.59) | MAPTTP53SMN1; SMN2POLBRXFP1 | |
| SCHEMBL429402 | 0.83 | ADORA2A (0.80) | MAPTTP53SMN1; SMN2POLBADORA2A | |
| SCHEMBL19000337 | 0.82 | TP53 (0.67) | MAPTTP53SMN1; SMN2POLBRXFP1 | |
| SCHEMBL10134544 | 0.81 | MAPT (0.63) | MAPTTP53SMN1; SMN2POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181568-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | Siga Technologies, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |