Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13438497 | 0.80 | CYP1A2 (0.33) | POLBAPOBEC3G | |
| SCHEMBL25467522 | 0.78 | NOS3 (0.36) | — | |
| SCHEMBL22020969 | 0.77 | GCGR (0.33) | — | |
| SCHEMBL21625512 | 0.77 | NOS3 (0.35) | POLB | |
| SCHEMBL27448149 | 0.74 | MAPT (0.37) | POLB | |
| SCHEMBL27326054 | 0.74 | NOS3 (0.35) | — | |
| SCHEMBL27448146 | 0.72 | KDM5A (0.38) | — | |
| SCHEMBL21637150 | 0.70 | MAPT (0.35) | — | |
| SCHEMBL26539121 | 0.70 | NOS3 (0.41) | — | |
| SCHEMBL19021948 | 0.68 | POLB (0.33) | POLBAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174653-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174653-A1 | TLR7/8 ANTAGONISTS AND USES THEREOF | TLR7, TLR8, TLR9 | POLB 1929/4885APOBEC3G 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.