Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL2004299 | 0.96 | SLC7A5 (0.42) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL8588119 | 0.96 | SLC7A5 (0.49) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL8588121 | 0.96 | SLC7A5 (0.49) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL3909625 | 0.95 | SLC7A5 (0.50) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL3909629 | 0.95 | SLC7A5 (0.50) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL8503630 | 0.90 | SLC7A5 (0.47) | SLC7A5ALOX15TPH1PTGS1ALPI | |
| Tyrosine SCHEMBL8503634 | 0.90 | SLC7A5 (0.47) | SLC7A5ALOX15TPH1PTGS1ALPI | |
| Tyrosine SCHEMBL26977289 | 0.87 | SLC7A5 (0.60) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL29061147 | 0.85 | SLC7A5 (0.42) | SLC7A5PTGS1ALPIPKMXIAP | |
| Dl-Tryptophan SCHEMBL26109782 | 0.85 | KDM4E (0.44) | ALOX15BLMPMP22KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496245-A2 | ANALOGS OF PITUTARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) AND METHODS FOR THEIR USE | The Administrators Of The Tulane (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011054001-A2 | ANALOGS OF PITUTARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE (PACAP) AND METHODS FOR THEIR USE | THE ADMINISTRATORS OF THE TULANE (US) | 2011-05-05 | — | — | WO | disclosed |
| US-20050164969-A1 | Method of extending life span | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-07-28 | — | — | US | disclosed |