Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | TPH1 | P17752 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL8588119 | 1.00 | SLC7A5 (0.49) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL1900124 | 0.96 | SLC7A5 (0.45) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL2004299 | 0.93 | SLC7A5 (0.42) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL3909629 | 0.91 | SLC7A5 (0.50) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL3909625 | 0.91 | SLC7A5 (0.50) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL26977289 | 0.90 | SLC7A5 (0.60) | SLC7A5ALOX15BLMPMP22KMT2A | |
| Tyrosine SCHEMBL20377367 | 0.88 | SLC7A5 (0.63) | SLC7A5ALOX15PTGS1ALPIPKM | |
| Tyrosine SCHEMBL3789572 | 0.87 | SLC7A5 (0.65) | SLC7A5ALOX15PTGS1ALPIPKM | |
| Tyrosine SCHEMBL3789569 | 0.87 | SLC7A5 (0.65) | SLC7A5ALOX15PTGS1ALPIPKM | |
| Tyrosine SCHEMBL9751837 | 0.87 | SLC7A5 (0.65) | SLC7A5ALOX15PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998047913-A2 | INHIBITION OF HIV-1 REPLICATION BY A TAT RNA-BINDING DOMAIN PEPTIDE ANALOG | THE UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 1998-10-29 | — | — | WO | disclosed |