Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23900960 | 0.91 | HDAC3 (0.36) | HPGDSMN1; SMN2HTTHDAC1HDAC3 | |
| SCHEMBL17229452 | 0.90 | HPGD (0.43) | HPGDSMN1; SMN2HTTHDAC1HDAC3 | |
| SCHEMBL16579861 | 0.88 | HDAC3 (0.46) | HPGDSMN1; SMN2HTTHDAC1HDAC3 | |
| SCHEMBL17232557 | 0.88 | SMN1; SMN2 (0.46) | HPGDSMN1; SMN2HTTHDAC1HDAC3 | |
| SCHEMBL26059967 | 0.87 | HDAC3 (0.42) | HPGDSMN1; SMN2HTTHDAC1HDAC3 | |
| SCHEMBL14274908 | 0.86 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2HTTHDAC1HDAC3 | |
| SCHEMBL17721383 | 0.85 | FOLH1 (0.43) | HPGDSMN1; SMN2HTTHDAC1HDAC3 | |
| SCHEMBL17721381 | 0.85 | ALDH1A1 (0.36) | SMN1; SMN2HTTHDAC1HDAC3HDAC4 | |
| SCHEMBL27340399 | 0.84 | HPGD (0.46) | HPGDSMN1; SMN2HTTHDAC1HDAC3 | |
| SCHEMBL14264529 | 0.84 | SMN1; SMN2 (0.43) | HPGDSMN1; SMN2HTTHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292961-B2 | Disulfur bridge linkers for conjugation of a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-21 | — | — | US | disclosed |
| US-10293055-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-21 | — | — | US | disclosed |
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10292961-B2 | Disulfur bridge linkers for conjugation of a cell-binding molecule | CD74, CD2, EPCAM | HPGD 2017/4885SMN1; SMN2 3882/4885HTT 4074/4885 |
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | AADAC, EPCAM, DCLRE1A | HPGD 608/4885SMN1; SMN2 4722/4885HTT 4446/4885 |
| US-10293055-B2 | Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule | AADAC, EPCAM, DCLRE1A | HPGD 608/4885SMN1; SMN2 4722/4885HTT 4446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.